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| Fig. 18.1 Vitiligo. A, African- American man with vitiligo. Note the complete loss of skin pigmentation of the hands and wrists. B, Segmental vitiligo. (Courtesy of James E. Fitzpatrick, MD.) |
Typically, lesions of vitiligo are stark white with a well-demarcated border and no other skin changes. Sometimes, the border is hyperpigmented and rarely erythematous. Areas commonly affected are the periorbital, perioral, and anogenital areas, as well as the elbows, knees, axillae, inguinal folds, and forearms. Frequently, lesions of vitiligo develop symmetrically on the trunk and extremities (Fig. 18-1A). Vitiligo also causes depigmentation of hair (leukotrichia). Less commonly vitiligo is focal or segmental (Fig. 18-1B).
