Immunosuppressant DrugsTopical ImmunosuppressantsTopical Glucocorticoids- Topical form: inhibits epidermal mitosis and DNA synthesis, ↓ collagen cross-linking
- Vasoconstriction directly proportional to anti-inflammatory potency of agent
- SE: atrophy, striae, acneiform eruption, hypertrichosis, hypopigmentation
- Tachyphylaxis: efficacy of topical lost over time; structurally different steroid required
- Pregnancy category C
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