Botulinum Toxin | | | | | | Core Messages -
Clostridium botulinum produces eight serologically distinct toxins: A, B, Cα, Cβ, D, E, F, G. Of the eight serotypes, A is the most potent. -
Botulinum toxin type A and type B are the only commercially available serotypes and are used for various medical indications, including cosmetic treatment. -
Botulinum toxin relaxes the underlying muscles of expression, leading to a reduction in the formation of skin creases. Over time, regular maintenance treatments can lead to the disappearance of these creases. -
Botulinum toxin is safe and effective in all skin types (Fitzpatrick I–VI). | | | | | | | The formation of crease lines and rhytids is a natural component of the aging process.As individuals enter their 30s and 40s, fine lines, creases, rhytids, and sagging skin become apparent, and deep furrows and frown/scowl lines often develop. Such furrows and frown/scowl lines are referred to as dynamic rhytids because they arise when we laugh, frown, or smile and are caused by the repeated forces generated by the underlying muscles. These hyperkinetic muscles include the frontalis (responsible for forehead furrows), corrugator supercilii (involved in frown/scowl lines), orbicularis oculi (responsible for crow’s feet), and procerus and depressor supercilii (also involved in frown/ scowl lines). The repetitive contraction of these muscles beneath the skin causes creases and rhytids [1]. Botulinum toxin, a natural purified protein, is used to relax these facial muscles of expression. |
