What are the clinical manifestations of blastomycosis?

An important concept of blastomycosis is that it can mimic many other disease processes and has been called “The Great Pretender.” The pulmonary manifestations range from a community-acquired pneumonia on one end of the spectrum to malignancy. Patients may have no pulmonary symptoms. Pulmonary disease is seen in 87% of patients, skin lesions in 20%, bone involvement in 15%, central nervous system in 5% to 10%, and less commonly the genitourinary system (prostate).