Are Lichen planus and bullous pemphigoid related?

Lichen planus pemphigoides is a rare skin disease that presents with overlapping features of LP and bullous pemphigoid. It is characterized by bullous lesions arising on lichen planus–like papules and also upon uninvolved skin. While the condition may arise de novo, particularly in children, it may also be induced by medications including: cinnarizine, captopril, ramipril, simvastatin, PUVA, antituberculous medications, and some Chinese herbs.

Cohen DM, Ben-Amitai D, Feinmesser M, Zvulunov A: Childhood lichen planus pemphigoides: a case report and review of the literature, Pediatr Dermatol 26:569–574, 2009.

Xu HH, Xiao T, He CD, et al: Lichen planus pemphigoides associated with Chinese herbs, Clin Exp Dermatol 34:329–332, 2009.