Is squamous cell carcinoma of the vulva associated with a precancerous state?

Yes. Vulvar intraepithelial neoplasia (VIN) is the term used to describe dysplasia of vulvar epithelial cells. VIN is further divided into VIN usual type, which is associated with high-risk human papilloma virus (HPV) strains, such as HPV 16 and HPV 18, and differentiated VIN, which is associated with chronic vulvar dermatoses, particularly lichen sclerosus. VIN is associated with vulvar pruritus and burning. The lesion may be described as a raised papule or nodule that is erythematous or white.

Maclean AB, Jones RW, Scurry J, Neill S: Vulvar cancer and the need for awareness of precursor lesions, J Low Genit Tract Dis 13:115–117, 2009.