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Fig. 23.5 Child with urticaria pigmentosa demonstrating multiple tan papules and a positive Darier’s sign in two lesions that have been stroked. (Courtesy of James E. Fitzpatrick, MD.) |
Darier’s sign is a finding in urticaria pigmentosa. In urticaria pigmentosa, yellow-tan to red-brown macules containing increased numbers of mast cells are scattered over the body. Stroking the skin over the pigmented macules causes an urticarial wheal to form that is limited to the area of the pigmented lesion (Fig. 23-5).