Thalidomide- Inhibits TNFα but exact mechanism unknown
- Treats: erythema nodosum leprosum, HIV associated mucosal ulceration, recalcitrant DLE or SCLE
- SE: fetal anomalies (phocomelia), peripheral neuropathy (proximal muscle weakness, painful paresthesias of extremities), somnolence, TEN, hypersensitivity reaction, leukopenia
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