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Fig. 64.2 Pemphigus vulgaris demonstrating erosive lesions of the lips and left cheek. (Courtesy of James E. Fitzpatrick, MD.) |
Pemphigus vulgaris is a superficial blistering disease that typically affects middle-aged individuals (Fig. 64-2). It often presents initially with mouth ulcerations (60% of cases) but can involve blistering on areas above the waist. Pemphigus vulgaris may present acutely and, in severe cases, may resemble TEN or Stevens-Johnson syndrome. Early diagnosis is important because this condition is usually fatal if untreated, and current therapies are effective.
Groves RW: Pemphigus: a brief review,
Clin Med 9: 371–375, 2009.