Table 4-6 Select Bartonella Infections |
| Disease | | Etiology/Vector | | Clinical Findings | | Treatment |
| Oroya Fever (Carrion’s disease) (Verruga peruana) (Peruvian wart) | | Bartonella bacilliformis
Vector: sandfly Lutzomyia verrucarum | | Biphasic disease - Acute stage (Oroya fever): fever + hemolytic anemia - Chronic stage (verruga peruana): erythematous papules/nodules, resolves spontaneously but may persist for years | | Acute stage: chloramphenicol (covers salmonella coinfection) Chronic stage: TCN or PCN |
| Cat-Scratch Disease | | Bartonella henselae
Vector: cat flea Ctenocephalides felis
Transmission via cat bite or scratch (flea feces inoculated into scratch site) | | Unilateral tender lymphadenitis 2–4 weeks after cat scratch, typically in axilla > epitrochlear node (can last between 2 and 5 months)
Parinaud oculoglandular syndrome: unilateral conjunctivitis and regional lymphadenitis | | Spontaneous resolution typical
If patient immunosuppressed, treat with doxycycline or erythryomycin |
| Bacillary Angiomatosis | | Bartonella henselae, Bartonella quintana
Vector:lice, ticks, fleas | | Erythematous tender papules and nodules resembling pyogenic granulomas, seen mainly in HIV patients | | Doxycycline or erythromycin |
| Trench Fever (Shinbone fever) | | Bartonella quintana Vector: body louse
Pediculus humanus var. corporis | | Fever (relapsing), chills, tenderness of shins, back pain, and transient macular eruption
↑ Risk: crowding and poor hygiene | | Doxycycline or erythromycin |
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