Content

»	Bacterial Infections
	»	Gram-positive Infections
		»	Staphylococcal Infections
			»	Impetigo
			»	Staphylococcal Scalded Skin Syndrome (SSSS)
			»	Toxic Shock Syndrome (TSS)
			»	Bacterial Folliculitis
			»	Furuncle, Carbuncle, Abscess
		»	Streptococcal Infections
			»	Cellulitis
			»	Erysipelas (St. Anthony’s Fire)
			»	Blistering Distal Dactylitis
			»	Necrotizing Fasciitis
			»	Perianal Streptococcal Disease
			»	Ecthyma
			»	Scarlet Fever
			»	Streptococcal Toxic Shock Syndrome (STSS)
		»	Corynebacterial Infections
			»	Erythrasma
			»	Trichomycosis Axillaris
			»	Pitted Keratolysis
			»	Cutaneous Diphtheria
		»	Other gram-positive Infections
			»	Anthrax (Malignant Pustule)
			»	Erysipeloid (Fish Handler’s Disease)
			»	Actinomycosis (“Lumpy Jaw”)
			»	Actinomycetoma (Madura Foot)
	»	Gram-negative Infections
		»	Pseudomonal Infections
			»	Green Nail Syndrome
			»	Ecthyma Gangrenosum
			»	Pseudomonas Hot Foot Syndrome
			»	Pseudomonal Folliculitis (Hot Tub Folliculitis)
			»	Pseudomonal Pyoderma
		»	Other gram-negative Infections
			»	Acute Meningococcemia
			»	Bartonella Infections
			»	Rickettsiae
			»	Spirochetes
			»	Syphilis (Lues, Venereal Syphilis)
	»	Mycobacteria
		»	Tuberculosis (TB)
		»	Leprosy (Hansen’s Disease)
		»	Atypical Mycobacteria
			»	M. marinum (Fish Tank Granuloma)
			»	M. ulcerans (Buruli Ulcer)
			»	M. fortuitum Complex
			»	M. avium -Intracellulare Complex (M. avium Complex, MAI)
			»	M. kansasii

Anthrax (Malignant Pustule)

Figure 4.12
A: Cutaneous diphtheria
(Courtesy of Public Health
Image Library: CDC)
B: Cutaneous anthrax
(Courtesy of James Steele,
CDC)
C: Erysipeloid
(Reprint from Mandell G, ed.
Atlas of Infectious Diseases.
Philadelphia PA: Current
Medicine LLC; 2002)

(Figure 4.12B)

Acute disease in humans and animals caused by Bacillus anthracis, a Gram-positive spore-forming rod
Clinical forms: cutaneous, pulmonary, and GI
Cutaneous form : “malignant pustule” at inoculation site which spreads and becomes hemorrhagic → central eschar with surrounding nonpitting edema → eschar sloughs leaving shallow ulceration
Virulence factors: capsule and two exotoxins: e dema toxin (increases cAMP levels) and lethal toxin (increases TNFα and IL1 β promoting shock/death)
Bioterorism-associated treatment: ciprofloxacin or doxycycline (conventional treatment: PCN)