Ichthyosis Vulgaris (IV) | Figure 2.32
A: Uncombable hair syndrome
(Reprint from Burgdorf WH,
Plewig G, Wolff HH,
Landthaler M, eds. Braun-
Falco’s Dermatology. 3rd ed.
Heidelberg: Springer; 2009)
B: Triangular lunulae (NPS)
(Reprint from Tosti A, Ralph
DC, Piraccini BM, Iorizzo M.
Color Atlas of Nails. Heidelberg:
Springer; 2010)
C: Ichthyosis vulgaris
(Courtesy of Dr. Paul Getz) |
(Figure 2.32C) - AD, decreased/absent profilaggin (keratohyalin granules)
- Presents few months after birth to early childhood with fine, white scales on extensor surfaces; flexures spared, hyperlinear palms/soles, atopic diathesis
- Histology: attenuated/absent granular layer, retention hyperkeratosis
- Acquired form of IV associated with internal disease, malignancies, and some medications
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