Mononuclear Phagocytes- Referred to as monocytes when in bloodstream but called macrophages when in tissue
- Identify pathogens using opsonin receptors, mannose receptors and TLRs; destroy pathogens via reactive oxygen intermediates and lysosomal enzymes
- Degrade foreign antigens or cells into peptides and present to T cells; produce cytokines
- Receptors/markers found on cell: Fc receptor for IgG, complement receptor, MHC II
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