Are there contraindications to using PUVA?

Contraindications include a history of psoralen hypersensitivity reactions; photosensitive diseases including lupus erythematosus, porphyria, xeroderma pigmentosum, and albinism; malignant melanoma; pregnancy; and aphakia (absence of a lens may produce retinal damage). PUVA photochemotherapy should be used with caution in patients with fair skin, a history of previous ionizing radiation, history of multiple skin cancers, cataracts, immunosuppression, uremia, or renal failure. Patients with severe myocardial or other diseases that may disallow standing for prolonged periods in the treatment cabinet may not be able to receive photochemotherapy.