« Back to Infections and Infestations

Bullous Viral Eruptions

»What do herpes simplex (HSV) virus and varicella-zoster virus (VZV) have in common?
»What happens during primary HSV infection?
»What about recurrent infection?
»What is the difference between a primary and an initial HSV infection?
»How is HSV transmitted?
»How long is incubation period for HSV (i.e., the time from initial infection to appearance of vesicles)?
»Define asymptomatic shedding.
»Can you be infected with HSV and not know it?
»How do HSV-1 and -2 differ?
»How do you diagnose HSV infection?
»How is a Tzanck smear performed?
»What are the drugs of choice for treatment of HSV?
»When is chronic suppressive therapy indicated?
»Are patients with genital herpes at greater risk for becoming infected with the human immunodeficiency virus (HIV)?
»What recommendations can you make to a patient with genital herpes to reduce the risk of transmission to his or her partner?
»Can HSV infect the skin in areas other than around the mouth or anogenital areas?
»How does a baby get herpes? Is it a serious problem?
»Describe the natural history of varicella.
»What is shingles?
»Can herpes zoster be recurrent?
»What is disseminated zoster?
»Is herpes zoster contagious?
»What is postherpetic neuralgia?
»How do you diagnose VZV infection?
»What is the treatment for varicella?
»How about herpes zoster?
»Should I be concerned about the patient with herpes zoster involving the tip of the nose?
»Who should get the herpes zoster vaccine?
»What is hand, foot, and mouth disease?
»What is orf?

 
 
 

Describe the natural history of varicella.


Varicella with skin lesions at all stages of development. (Courtesy of Joseph G. Morelli, MD.)
Fig. 25.3 Varicella with skin lesions at all stages of development. (Courtesy of Joseph G. Morelli, MD.)
Varicella, or chickenpox, is the primary infection with varicella-zoster virus (VZV). It is characterized by the appearance of two to three successive crops of diffuse, pruritic vesicles and papules over several days. These lesions then evolve into pustules and crusted erosions, so that lesions in all stages of development are present together (Fig. 25-3). Lesions generally persist for up to 1 week.

Varicella most commonly occurs during childhood. It is highly contagious, both via respiratory secretions and contact with the cutaneous lesions. The incubation period ranges from 10 to 23 days, and the patient is considered contagious from 4 days before the onset of lesions until all lesions have crusted.