What are targetoid (target) lesions?

Fig. 2.4 Targetoid lesions. Patient with classic erythema multiforme demonstrating lesions resembling a 'bull’s-eye' Note that some lesions demonstrate a small, centrally placed blister. (Courtesy of the Fitzsimons Army Medical Center teaching files.)

Targetoid lesions typically consist of three zones. The first zone consists of a dark or blistered center (bull’s-eye) that is surrounded by a second, pale zone. The third zone consists of a rim of erythema. Target lesions classically are found in patients with erythema multiforme (Fig. 2-4).