Content

»	Soft Tissue Augmentation
	»	Introduction
		»	Overview of Common Injectable Fillers
			»	Fat
			»	Autologous
			»	Cadaver-Derived
			»	Collagen
			»	Hyaluronic Acid
			»	Poly-L-lactic Acid
			»	Silicone Oil
	»	Scientific Background
		»	Autologous Material
			»	Fat Transfer
			»	Fat Autograft Muscle Injection
			»	Cultured Human Fibroblasts
		»	Cadaver-derived Implants
			»	Acellular Allogeneic Dermis
			»	Injectable Microparticulate Acellular Allogeneic Dermis
			»	Lyophilized Human Particulate Fascia Lata
		»	Temporary
			»	Animal-Based Collagen
			»	Non-Animal-Based Collagen
			»	Hyaluronic Acid
			»	Poly-L-lactic Acid
		»	Semipermanent
			»	Synthetic Calcium Hydroxylapatite Microspheres Suspended in Aqueous Polysaccharide Gel
		»	Permanent
			»	Polymethylmethacrylate Microspheres in Denatured Bovine Collagen
			»	Silicone Oil
		»	Implants
			»	Expanded Polytetrafluoroethylene
			»	Gore-Tex
			»	Dual-Porosity Expanded Polytetrafluoroethylene
	»	Indications
	»	Patient Selection
		»	Contraindications
		»	Specific Product Contraindications
	»	References

Poly-L-lactic Acid

Poly-L-lactic acid (PLA) is a sterile synthetic polymer that is biodegradable and biocompatible. Once injected into the deep dermis, the PLA microparticles stimulate the formation of collagen. It has been approved in Europe since 1999 for soft tissue augmentation and is currently approved in the United States for HIV-associated lipoatrophy.