Nail Diseases

   
 
Table 3-31 Nail Disorders
 EntityClinical FindingsAssociated Diseases
Nail matrix
 
Beau’s lines
(Figure 3.58D)
Transverse depression in nail plate
surface
Severe systemic event (all nails) or
trauma/disease of matrix (single nail)
 
Hapalonychia
 
Soft nail plate
  
 
Koilonychia
(Spoon nails)
Thin, concave nails with eversion of free nail edge
Hereditary, physiologic (children), iron deficiency, thyroid abnormality
 
Leukonychia, diffuse
Opaque or completely white nail plate
Chemotherapy, white superficial
onychomycosis, congenital disease
 
Leukonychia, punctate
White macules on nail plate
Psoriasis (PSO), trauma to matrix
 
Leukonychia, transverse
(striate) (Figure 3.57E)
 
Narrow white transverse lines along nail plate
 
Trauma to matrix
 
Mee’s lines
Transverse lines of entire nail breadth in all nails
Arsenic poisoning, trauma, medications, severe illness, PSO (flare)
 
Onychomadesis
(Nail shedding)
Detachment of nail plate from proximal nail fold (PNF) → shedding of nail
Traumatic, medications (i.e. chemo), drug reaction (i.e. TEN), autoimmune diseases, systemic illness
 
Onychorrhexis
(Figure 3.58E)
Longitudinal ridging, ± fissuring of plate
Lichen planus, chronic trauma, repeated wet/dry cycles, normal with aging
 
Pitting
(Figure 3.57A)
Punctate depressions of nail plate surface

{Elkonyxis: large 2-mm pits}
Psoriasis (PSO), alopecia areata,
eczema
 
Red lunula
Pink to red spots within lunula
Alopecia areata, rheumatoid arthritis, LE, CHF, CO poisoning
 
Trachyonychia (20 nail
dystrophy) (Figure 3.57C)
 
Rough, thinned nails with longitudinal ridging
 
Alopecia areata, lichen planus (LP), PSO, eczema
Nail bed
 
Apparent leukonychia
White discoloration (fades with pressure); nail plate looks white but normal color
Drugs (i.e. chemo agents) or systemic disease
 
Oil spots
(Figure 3.57B)
 
Brown spots under nail plate
 
PSO
 
Onycholysis
(Figure 3.57F)
White discoloration at distal end where nail plate separated from bed
PSO, trauma, onychomycosis, medications (TCN, NSAID, PUVA), tumors, systemic diseases (hyperthyroidism), pregnancy
 
Splinter hemorrhages
(Figure 3.59A, B)
 
Rough, thinned nails with longitudinal ridging
 
Alopecia areata, lichen planus (LP), PSO, eczema
Nail color
 
Half and half nails
(Lindsay’s nails)
(Figure 3.59C)
Proximal ½ with white zone, distal ½ with red-brown zone
Chronic renal disease
 
Hutchinson’s sign
Periungual black discoloration
Melanoma
 
Muehrcke’s bands
 
Transverse white bands parallel to lunula
 
Hypoalbuminemia, chemotherapy
 
Melanonychia
Partial or diffuse
Drugs, melanoma, Laugier-Hunziker
 
Longitudinal melanonychia
(Melanonychia striata)
(Figure 3.58F)
Vertical brown-black band (proximal to distal margin)

{Common in darkly pigmented skin types}
Nevus, lentigo, drugs, trauma, melanoma
 
Terry’s nails
(Figure 3.59D)
Proximal 2/3 white nail color, distal
1/3 brown-pink band
Cirrhosis, hypoalbuminemia, diabetes, cardiac disease
Others
 
Absent lunula
No visible lunula
Yellow nail syndrome, renal failure, trauma
 
Anonychia
Absence of nail
Nail patella syndrome, COIF, (Congenital Onychodysplasia of the Index Finger) scarring
 
Blue lunula
Blue discoloration of lunula
Wilson’s, drugs, PUVA, argyria, etc.
 
Brachyonychia
 
Short, wide nails
 
Rubinstein-Taybi syndrome, PSO
 
Clubbing
↑ Nail curvature w/ bulbous growth of tip of digit
Chronic pulmonary disease, idiopathic, familial, systemic disease
 
Dolichonychia
 
Long nails
 
Marfan’s, Ehlers Danlos, etc.
 
Dorsal pterygium
(Figure 3.58C)
Wing-like growth fusing PNF with nail bed/matrix
Lichen planus, epidermal bullosa, TEN, GVHD, TEN, cicatricial pemphigoid
 
Habit tic deformity
(Figure 3.58A)
 
Parallel horizontal grooves
 
Caused by repetitive trauma to cuticle
 
Macronychia
Large nails
Congenital abnormality
 
Median canaliform dystrophy
(Figure 3.58B)
Inverted ‘fir tree’(oblique lines from midline defect)
Idiopathic or inherited
 
Micronycha
Small nails
Congenital defect (i.e. COIF)
 
Onychauxis
 
Hypertrophic nail plate
 
May be due to chronic trauma
 
Onychoatrophy
Reduction in size and thickness of nail plate
LP, vascular insufficiency, systemic disorders, medications
 
Onychocryptosis
 
Ingrown nail
  
 
Onychogryphosis
Grossly thickened and long nail, resembling claw
Inability to cut toenails, long-term pressure (i.e. shoes), neglect
 
Onychophagia
 
Nail biting
  
 
Onychoschizia
(Lamellar nail splitting)
Distal lamellar separation into horizontal layers
Repeated wet and dry cycles, trauma, systemic disease and medications
 
Onychotillomania
 
Chronic picking of nail
  
 
Pachyonychia
Thickened nails
Pachyonychia congenita
 
Pincer nails
 
Overcurvature lateral portion
 
Pressure (ill-fitting shoes), hereditary
 
Platyonychia
Flat nail
Inherited or acquired
 
Racket nails
 
Distal phalanx short/wide
 
Form of brachyonychia
 
Subungual exostosis
(Figure 3.59E, F)
Painful, bony subungual growth elevating nail plate
X-ray confirms bony exostosis
 
Triangular lunula
 
Triangular shape of lunula
 
Nail-patella syndrome
 
Ventral pterygium
(Pterygium inversum unguis)
Fusion of hyponychium to distal nail plate
Familial, trauma, systemic sclerosis, lupus erythematosus
 
Yellow nails
Yellow color to nail plate
Yellow nail syndrome, drugs, chronic enamel

{Yellow nail syndrome: pulmonary disorder + lymphedema + yellow, slow growing nails with absent lunulae}
 
V-shaped nicking
(Figure 3.57D)
V-shaped nick at free margin
Darier disease
      
 
   
Figure 3.57 A: Pitting B: Pitting, ‘oil spots’ and onycholysis (psoriatic nail) C: Trachyonychia D: Darier nail (v-shaped nicking) (Courtesy of Dr. Paul Getz) E: Leukonychia striata (Courtesy of Dr. Paul Getz) F: Onycholysis (Courtesy of Dr. Paul Getz)
Figure 3.57
A: Pitting
B: Pitting, ‘oil spots’ and onycholysis (psoriatic nail)
C: Trachyonychia
D: Darier nail (v-shaped nicking)
(Courtesy of Dr. Paul Getz)
E: Leukonychia striata (Courtesy of Dr. Paul Getz)
F: Onycholysis (Courtesy of Dr. Paul Getz)
 
Figure 3.58 A: Habit tic deformity B: Median nail dystrophy C: Dorsal pterygium in lichen planus (Reprint from Tosti A, Ralph DC, Piraccini BM, Iorizzo M. Color Atlas of Nails. Berlin: Springer; 2010) D: Beau’s lines (Courtesy of Dr. Paul Getz) E: Onychorrhexis (longitudinal ridging) F: Melanonychia striata (Courtesy of Dr. Sophie M. Worobec)
Figure 3.58
A: Habit tic deformity
B: Median nail dystrophy
C: Dorsal pterygium in lichen planus
(Reprint from Tosti A, Ralph DC, Piraccini BM, Iorizzo M. Color Atlas of Nails. Berlin: Springer; 2010)
D: Beau’s lines (Courtesy of Dr. Paul Getz)
E: Onychorrhexis (longitudinal ridging)
F: Melanonychia striata
(Courtesy of Dr. Sophie M. Worobec)

Figure 3.59 A: Splinter hemorrhage (Courtesy of Dr. Paul Getz) B: Splinter hemorrhage C: Half-half nails D: Terry’s nails (Reprint from Tosti A, Ralph DC, Piraccini BM, Iorizzo M. Color Atlas of Nails. Berlin; Springer; 2010) E: Subungual exostosis (Courtesy of Dr. Paul Getz) F: Subungual exostosis (Courtesy of Dr. Paul Getz)
Figure 3.59
A: Splinter hemorrhage (Courtesy of Dr. Paul Getz)
B: Splinter hemorrhage
C: Half-half nails
D: Terry’s nails
(Reprint from Tosti A, Ralph DC, Piraccini BM, Iorizzo M. Color Atlas of Nails. Berlin; Springer; 2010)
E: Subungual exostosis (Courtesy of Dr. Paul Getz)
F: Subungual exostosis (Courtesy of Dr. Paul Getz)