Erythema Elevatum Diutinum (EED) | Figure 3.42 A: Urticarial vasculitis (Courtesy of Dr. Iris K. Aronson) B: EED* C: Granuloma faciale* * Reprint from Burgdorf WH, Plewig G, Landthaler M, Wolff HH, eds. Braun-Falco’s Dermatology. 3rd ed. Heidelberg: Springer; 2009 |
(Figure 3.42B) - Presents with red, violaceous or brown papules and plaques favoring extensor surfaces; associated arthralgias
- Histology: LCV with neutrophilic infiltrate in early lesions; fibrosis and lipid deposits with cholesterol clefts in older lesions
- Associated with autoimmune diseases, infections (hemolytic strep, HBV, HIV), inflammatory bowel disease, hematologic disorders (IgA monoclonal gammopathy); lesions thought to be related to immune complex deposition in blood vessels with damage to vessels
- Treatment: d apsone treatment of choice
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