Erythema Toxicum Neonatorum

• Onset typically 24 – 48 h after birth; occurs in half of all full-term infants
• Presents with blotchy erythematous macules, papules, pustules, and wheals
• Smear of sterile vesicle/pustule shows eosinophils
• Histology: subcorneal pustules with eosinophils, associated with pilosebaceous unit