Lamina lucida- Electron-lucent zone under hemidesmosome on EM; weakest link of BMZ
- Comprised of anchoring filaments (laminin-332), laminin-1, fibronectin, nidogen (entactin), uncein, and portion of BPAG2
Anchoring Filaments- Delicate filaments emanating perpendicularly from HD which stretch from plasma membrane to lamina densa; product of basal keratinocytes; smaller than anchoring fibrils
- Laminin-332: also known epiligrin (truncated laminin), laminin-5, kalinin, and nicein; glycoprotein serving as major component of anchoring filaments; major attachment factor for keratinocytes and binds α 6 β 4 integrin at hemidesmosome
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