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| Fig. 60.2 Pemphigoid gestationis. A, Umbilical urticarial plaques and tense blisters in a woman with pemphigoid gestationis. B, Intertriginous area between fingers demonstrating tense blisters. This is another commonly affected site in pemphigoid gestationis. (Courtesy of the Fitzsimons Army Medical Center teaching files.) |
Pemphigoid gestationis (also called herpes gestationis or gestational pemphigoid) is an autoimmune subepidermal bullous disorder of pregnancy that may start in the 2nd trimester, the 3rd trimester, or in the postpartum period. The skin lesions are characterized by urticarial papules and plaques, which then progress into painful bullae. The lesions of pemphigoid gestationis initially present periumbilically (Fig. 60-2A), and then spread to involve the trunk and extremities (Fig. 60-2B), usually sparing the face.
Semkova K, Black M: Pemphigoid gestationis: current insights into pathogenesis and treatment,
Eur J Obstete Gynecol Reprod Biol 145(2):138–144, 2009.
