Is Mohs surgery still performed with the zinc chloride chemical paste?

Very rarely. The technique has evolved to use fresh frozen tissue methods. In the 1970s, the use of frozen sections alone in Mohs surgery was shown to have comparable cure rates to the use of zinc chloride paste. The elimination of zinc chloride paste allowed Mohs surgery to take place in a single day and avoided the pain associated with paste application. In addition, the use of frozen sections made it possible for reconstruction of the Mohs defect to occur the same day as tumor removal.