Nicotinamide This is a physiologically active form of nicotinic acid which is thought to have anti-inflammatory, bacteriostatic effects on P. acnes and reduce sebum production. It is therefore most useful if there are inflammatory lesions in evidence. How to use nicotinamide? It should be applied to clean skin twice daily, preferably in the morning and evening. It may take up to 12 weeks to have a beneficial effect. |
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