How common are the congenital ichthyoses? How are they inherited? Ichthyosis vulgaris: Incidence of 1:250; autosomal dominant X-linked ichthyosis: Incidence of 1:6000; X-linked recessive Epidermolytic hyperkeratosis: Incidence of 1:300,000; autosomal dominant Congenital ichthyosiform erythroderma (CIE): Incidence of 1:100,000; autosomal recessive Lamellar ichthyosis: Incidence of 1:300,000; autosomal recessive Harlequin fetus: Rare; autosomal recessive Akiyama M: The clinical spectrum of nonbullous congenital ichthyosiform erythroderma and lamellar ichthyosis, Clin Exp Dermatol 28(3):235–240, 2003. DiGiovanna J: Ichthyosis: etiology, diagnosis, and management, Am J Clin Dermatol 4(2):81–95, 2003. Shwayder T: Disorders of keratinization: diagnosis and management, Am J Clin Dermatol 5(1):17–29, 2004. |
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