Tape Compression Blister Formation

This relatively uncommon cutaneous condition may occur when a tape dressing is applied to an area of tissue movement, such as the posterior calf, medial thigh, and popliteal fossae. The blister usually appears as a flaccid fluid-filled sack overlying normal-appearing skin. While these blisters can occur in response to the use of any tape, they occur more often when a 3M Microfoam tape is used. The tension with which this tape is typically applied increases the likelihood of blistering. Other variables that instigate blistering are hot weather conditions and thin and fragile skin.

It is important to take time and explain this reaction to the patient and to distinguish it from sclerotherapy-induced cutaneous necrosis or cutaneous infection. Early cutaneous necrosis may appear as a superficial blister. However, the underlying and adjacent tissue is usually indurated and erythematous. Bullous impetigo can have a similar appearance, but the underlying skin is usually warm and erythematous. The patient might also incorrectly assume that the blisters are an allergic reaction to the sclerosant. Fortunately, adhesive tape blisters resolve without any adverse sequelae within 1–2 weeks. The use of an occlusive hydroactive dressing, such as Duoderm, can aid in healing, prevent infection, and alleviate pain.