Botox Cosmetic Botox Cosmetic was approved by the FDA in April 2002 for the temporary improvement in the appearance of moderate to severe glabellar lines in men and women 65 years of age or younger.While the approval specifically applies to the vertical lines between the eyebrows, there are numerous reports in the literature where other rhytids, such as crow’s feet, horizontal forehead lines, neck lines, melolabial folds, and other hyperkinetic facial lines, have also been successfully treated [14, 15]. |
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