Specif Cells and Markers
| | | | | | | Table 8-3 Specific Cells and Markers | | | Cell type | | Markers | | | Macrophage | | α 1-antitrypsin, lysozyme, HAM 56, CD 68 | | | Melanocyte | | S100, HMB 45, mart1/melanA, vimentin | | | Langerhans cell | | S100, CD1a, vimentin | | | Merkel cell | | CK20, neurofilament, chromogranin A, NSE, synaptophysin, ± EMA | | | Sebaceous gland | | EMA, keratin | | | Sweat gland | | CEA, EMA, keratin (cytoplasmic positivity), gross cystic disease fluid protein-15 (in apocrine and some eccrine), smooth muscle actin (in myoepithelial cells) | | | Fibroblast | | Vimentin | | | Mast cell | | CD117 (c-kit) | | | Myofibroblast | | Muscle-specific actin, desmin (sometimes) | | | Dermal dendrocytes | | Factor XIIIa | | | Blood vessels | | Factor VIII–related Ag, CD31, CD34, vimetin | | | Nerves | | Axons: neurofilament, NSE | | | | Schwann cells: S100, GFAP, myelin basic protein (MBP) | | | Muscle | | Smooth muscle actin | | | | | |
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