Gout

Figure 3.20 A: Tuberous xanthoma* B: Tendinous xanthoma* C: Eruptive xanthoma* *Courtesy of Dr. Paul Getz
Figure 3.20
A: Tuberous xanthoma*
B: Tendinous xanthoma*
C: Eruptive xanthoma*
*Courtesy of Dr. Paul Getz
  • Recurrent attacks of acute inflammatory arthritis
  • Due to hyperuricemia → deposition of needle-like crystals of monosodium urate in skin and joints
  • Presents with firm, skin-colored to white-yellow dermal or subcutaneous papules or nodules (tophi), ± ulcerated surface with drainage of chalky material or white flecks
  • Negative birefringence under polarized light