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| Fig. 36.7 A, Eruptive xanthomas demonstrating typical yellow-brown papules. This patient’s triglyceride level was 7760. B, Tuberous xanthoma manifesting as a large nodular xanthoma of the knee. (Courtesy of James E. Fitzpatrick, MD.) |
Eruptive xanthomas are multiple, small, skin-colored to yellow-brown papules that occur in crops, most commonly on the buttocks, thighs, or elbows (Fig. 36-7A). On biopsy, there is accumulation of triglyceride within histiocytes and around blood vessels in the skin. These distinctive papules are a cutaneous sign of very high triglyceride levels. These patients are at risk to develop pancreatitis, which may be severe. Often, eruptive xanthomas are precipitated by the new onset of diabetes.
Naik NS: Eruptive xanthomas,
Dermatol Online J 7:11, 2001.
