How is 20-nail dystrophy related to Lichen planus? The etiology of 20-nail dystrophy is controversial. This destructive nail disorder affects mostly children, and it is not commonly associated with cutaneous lesions. Typically, all nails show excessive longitudinal ridging, with thin, brittle, opalescent nails. While some experts consider LP to be a possible etiology, other studies utilizing nail biopsy have demonstrated a spongiotic pattern of inflammation rather than a lichenoid process. The condition often results in permanent nail loss, and urgent consultation with a nail specialist is indicated. Yokozeki H, Niiyama S, Nishioka K: Twenty-nail dystrophy (trachyonychia) caused by lichen planus in a patient with gold allergy, Br J Dermatol 52:1087–1089, 2005. |
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