Angiofibroma (Fibrous Papule)

Figure 5.2
A: Dermatofibroma
(Courtesy of Dr. Paul Getz)
B: Dermatofibroma
C: Pearly penile papules

(Figure 5.2C)

General term for lesions with similar histologic features and includes periungual fibromas, fibrous papules and pearly penile papules
Presents as skin-colored to red solitary dome-shaped papule most often on nose or central face; pearly penile papules present as dome-shaped small papules circumferentially around corona of glans penis
Multiple angiofibromas seen in tuberous sclerosis
Histology: dome-shaped papule with ↑ fibroblasts, collagen oriented concentrically around follicles or perpendicular to epidermis, ↑ dilated blood vessels